Louis A. Cona M.D.
A brief description of MS and how mesenchymal stem cells may be able to aid in the management of MS symptoms and possibly even halt the progression of the disease.
Multiple sclerosis (MS) is a major cause of neurological disability. It is characterised by damage throughout the brain and spinal cord, with loss of myelin and myelinating cells and damage to neurons and axons. MS is the most common neurological disease in young adults, affecting approximately two million people worldwide. Currently there is no cure for MS. The standard treatment of MS involves disease-modifying drugs, which often work to alleviate the symptoms of MS, but not curing the underlying issues. However, these drugs carry adverse side effects and are ineffective in preventing disease progression in many MS patients.
Today Multiple Sclerosis is incurable, but stem-cell therapy might offer valuable therapeutic potential. Stem Cell therapy is currently demonstrating efficacy in treating patients with variable disease severity, with the best results in early-stage rapidly progressing MS patients with active CNS inflammation. Due to the urgency in treatment required of MS patients, all forms of stem cell therapy should be pursued. A strong rationale for cell-based therapy in multiple sclerosis is based on the ability of stem cells of neural and mesenchymal origin to decrease neuro-inflammation, to enhance repair processes, and perhaps to participate directly in remyelination, repair of damaged neurons.
Mesenchymal stem cells (MSCs) are precursor cells, or cells that can be isolated from adipose tissues(fat), bone marrow, and umbilical cord tissue. They are then culture-expanded to increase cell numbers up to 300 million, many times the volume of the original sample. This drastic increase in cell number ensures maximum effectiveness during treatment.
The stem cells will then be attracted to those areas of injury or inflammation and begin the process of differentiation to begin the healing process. Stem cells have demonstrated healing and repair-promoting properties. This makes MSCs an attractive potential therapy for MS and other conditions characterised by inflammation and/or tissue injury. Mesenchymal stem cells (MSCs) represent an attractive alternative to develop a cell-based therapy for MS. Other potential advantages of stem cell therapy to MS patients include their ability to move from the bloodstream to areas of injured tissues, allowing for a comfortable IV administration of these cells into the body. Stem cell therapies are generally less invasive, have shorter recovery times, and lasting healing effects on the body.
DVC Stem has been offering stem cell therapies for years. Our protocols are all IRB approved, and our cells come from well regulated, U.S. based, FDA compliant laboratories. We only offer high quality products and tried and tested treatments to our patients.
You can learn more about our MS protocols here: www.dvcstem.com/conditions/multiple-sclerosis
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