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Blog / Stem Cells

Anti-Aging Effects of Mesenchymal Stem Cell Therapy in 2021

Can stem cell therapy cure aging? This article looks at the possible benefits of stem cell therapy in regard to slowing the aging process.

Updated:

July 22, 2021

Anti-Aging Effects of Mesenchymal Stem Cell Therapy in 2021

David Lyons

Guest contributor

Jul 22, 2021

Louis A. Cona, MD

Medical Director | DVC Stem

Can stem cell therapy cure aging? This article looks at the possible benefits of stem cell therapy in regard to slowing the aging process.

Anti-aging effects of mesenchymal stem cells

With our current knowledge of stem cells, it is technically feasible to delay aging and improve both health and lifespan. Stem cells can play a crucial role in delaying the aging process. Stem cells, in combination with anti-aging genes, can create a sophisticated shield, which can prevent the effects of aging.

Increased wear and tear of the body’s natural stem cells, increases cellular damage, and accelerate the natural process of aging. Stem cells combined with anti-aging genes can potentially absorb the process of cellular aging. The introduction of “youthful” stem cells into the human body can rejuvenate existing cells and allow the body to age more gracefully & even reverse some effects of the aging process.

As we age, our cells get sick and die. When a cell dies, it creates a cascade of events, leading to inflammation and disease that can decrease the human lifespan. 


With our current knowledge of stem cells, it may be possible to test interventions that significantly delay aging. 


Many environmental factors accelerate aging, such as stress, pollution, lifestyle, injuries, disease, and exposure to toxins. A recently published study reviewed evidence that delaying and reversing aging in cells is feasible. Epigenetic (non-genetic influences on gene expression) changes drive aging, and reversal of these changes extend lifespan. (1) Epigenetic control of gene expression occurs by chemical modification of DNA. By choosing an active lifestyle and decreasing harmful environmental factors, aging can be delayed. 

So, what are stem cells?

Stem cells are the body's raw materials — cells from which all other cells with specialized functions are created. Mesenchymal stem cells are adult stem cells that have self-renewal, immunomodulatory, anti-inflammatory, signaling, and differentiation properties.  Mesenchymal stem cells (MSCs), self renewal capacity is characterized by their ability to divide and develop into multiple specialized cell types present in a specific tissue or organ.

Mesenchymal stem cells (MSCs) can be sourced from a variety of tissue including adipose tissue (fat), bone marrow, umbilical cord tissue, blood, liver, dental pulp, and skin.  

MSCs are widely used in the treatment of various diseases due to their self-renewable, differentiation, anti-inflammatory, and immunomodulatory properties. In-vitro (performed in a laboratory setting) and in-vivo (taking place in a living organism) studies have supported the understanding mechanisms, safety, and efficacy of MSC therapy in clinical applications. (3)

According to a recent study conducted by Biehl et al., “The two defining characteristics of a stem cell are perpetual self-renewal and the ability to differentiate into a specialized adult cell type.” (1)

The benefits of a stem cell transplant for aging

  • A feeling of vitality and rejuvenation 
  • Improved capacity for physical activities
  • Thickening and improved quality of hair
  • Increased libido
  • A decrease in pain
  • Increased strength, balance & overall mobility
  • Enhanced immunity 
  • Overall improvement in the quality of life
  • Immune system regulation


How stem cell therapy reduces inflammation, at a cellular level

Mesenchymal stem cells can influence the processes of white blood cells.  A macrophage is a large white blood cell that is an integral part of our immune system. Macrophages are a type of blood cell that removes infectious agents and dead cells from the blood that can create inflammation (M1) and reduce inflammation (M2). 

M1 macrophages are associated with accelerated aging, and M2 macrophages are associated with anti-aging. Mesenchymal stem cells shift M1 macrophages to M2. They are, therefore, giving the human body more tools to combat the natural aging process by significantly reducing inflammation.


Stem cells can maintain mitochondrial health

Cord tissue-derived mesenchymal stem cells also maintain mitochondrial health (the powerhouse of the cell) by intercellular communication through tunneling nanotubes. This system senses the mitochondrial status of patient’s cells and physically transfers mitochondria from stem cells to unhealthy cells. 

DVC Stem aims to increase this process by providing patients with a two month supply of Vitrobiopharma’s STEMulize™ stem cell supplement.  According to Vitro Biopharma, this supplement promotes the expression of the anti-aging gene SIRT-1 by 200-300-fold, resulting in life extension. STEMulize™ also increases the expression of genes involved with stem cell differentiation capacity, migration, and production of proteins responsive to stress that provide cellular protection.   


Stem cell anti aging, how our cells age

Aging is a complex, natural process; the effect of environmental factors, genetics, and routine wear and tear on the bodies eventually takes a toll in a multitude of different ways. It is this result of living life that can bring unavoidable health problems. Over time, the cells of the body age as we do, resulting in their inability to replicate; they become damaged and die. The loss of efficient cell replication is what causes our bodies to age. 


What are the 10 signs of aging?

Some of the most common signs of aging are: 

  • Impaired vision
  • Impaired hearing
  • Loss of strength in muscles
  • Loss of bone density
  • Decreased immune system function
  • Decreased cognitive ability 
  • Less efficient metabolism.
  • Loss of energy
  • Hair loss
  • Decreased balance and overall mobility


Stem cell therapy for anti aging

Aging cells can contribute to disease. Thus if cell aging can be prevented, slowed down, or even reversed, many diseases could be better managed. Stem cells may have the ability to slow this process down & combat certain age-related conditions. 


How do stem cells slow the aging process?

With stem cell therapies, you are replenishing the supply of stem cells to allow the body to repair and rejuvenate all the organs of your body. 

Stem cells possess unique factors that aid in anti-aging by helping our bodies regenerate cellular tissues, such as:

  • Skin
  • Joints
  • Bones
  • Organs 

This advanced therapy may be able to repair tissue that has been damaged by stress, injury, and environmental factors.


What is stem cell treatment?

During stem cell treatment at DVC Stem (stem cell clinic located in Grand Cayman), a patient receives approximately 300 million stem cells. These stem cells are harvested from umbilical cord samples, all of which undergo an extensive amount of testing to assure sterility and viability (percentage of live cells).

DVC Stem then packages the stem cells and store them in a cryogenic form (colder than 100 degrees below zero). At the time of intravenous administration, the cells are thawed to body temperature in a sterile lab and administered over several hours by our highly trained physicians. 

The high quantity of 300 million cells not only covers daily losses that have been occurring progressively for years but replaces the cellular losses a thousand times over.

A stem cell transplant aims to replace the reserve of the stem cells practically lost over the last 15 - 20 years.  After such a significant cell replenishment, the body’s organs are rejuvenated and renewed. 


Patients who undergo stem cell therapy for anti aging can usually expect: 

  • A feeling of vitality and rejuvenation 
  • Improved capacity for physical activities
  • Thickening and improved quality of hair
  • Increased libido
  • A decrease in pain
  • Increased strength
  • Enhanced immunity 
  • Overall improvement in the quality of life

Can stem cells cure aging?

With our current knowledge of stem cells, it is technically feasible to delay aging and improve both health and lifespan. Stem cells can play a crucial role in delaying the aging process. Stem cells, in combination with anti-aging genes, can create a sophisticated shield, which can prevent the effects of aging.

Increased wear and tear of the body’s natural stem cells, increases cellular damage, and accelerate the natural process of aging. Stem cells combined with anti-aging genes can potentially absorb the process of cellular aging. The introduction of “youthful” stem cells into the human body can rejuvenate existing cells and allow the body to age more gracefully & even reverse some effects of the aging process.

What is Stem Cell Rejuvenation?

Stem cell rejuvenation is a type of therapy used to combat the effects of the natural aging process. A large amount of youthful stem cells are injected into the patient via IV. These are intended to replace ones existing “old” cells, thus allow to body to work my efficiently by healing itself and reducing inflammation. 


So can you cure aging?

There is not enough clinical data to be able to state whether or not stem cells may be able to cure aging.  However, it may be possible to slow the aging process by following the above considerations.   


Find out if you are eligible for anti-aging stem cell therapy at DVC Stem


References:

(1) Rožman, P. (2019, July 19). How Could We Slow or Reverse the Human Aging Process and Extend the Healthy Life Span with Heterochronous Autologous Hematopoietic Stem Cell Transplantation. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/31203790

(2) Tonrey, T. (2019, April 11). Stem Cell Activation by Natural Products. Retrieved from https://vitrobiopharma.com/stem-cell-activation-by-natural-products/

"Dr. Cona is a leading edge stem cell treatment physician"

Matthew Murry - MS Patient

2 DAYS POST TREATMENT

"Is the video I posted from this morning! My speech is so easy for me now, got easier throughout the day! I can talk like a NYer (fast) for the first time in years! Praise God!"

- Matthew Murry

EXCITING IMPROVEMENTS

Only 3 days after treatment, Matthew is now able to touch his nose with his eyes closed as well as touch his thumb and pinky together. Both of which he was previously unable to do before treatment.

We are excited to see his continued progress. His story will be updated here so keep an eye out!

Matthew showing his progress with mobility

Matthew Murry - 3 days post treatment

"This is exciting stuff, god bless"

Matthew Murry - MS Patient

2 WEEKS POST TREATMENT

Matthew experiences sensation in the bottom of his feet after receiving a simple nerve test.

His left foot did not experience any sensation or move at all, but what happened to his right foot is extremely exciting!

50 DAYS POST TREATMENT

Matthew is now able to lift his leg unassisted. He was previously unable to do so.

Matthew is experiencing the benefits of stem cell therapy first hand. You can view his progress video here.


Matthew showing some amazing mobility improvements.

Matthew Murry - 50 days post treatment

"Amazing progress from one of our MS patients Matthew Murray"

Louis A. Cona, MD - DVC Stem

3 MONTHS POST TREATMENT

Matthew is able to stand up with the assistance of stability bars.

David Lyons

Multiple Sclerosis

Although David Lyons was able to successfully fight Multiple Sclerosis through a strict regimen of diet and exercise, he wanted to ensure he was doing everything he could to stay fit. Multiple Sclerosis can be managed with treatment, but there is currently no cure for the disease. For that reason, David came to DVC Stem years ago to use the regenerative and anti-inflammatory attributes of stem cells to aid in his fight for fitness.

The positive results he experienced enabled David to stay strong in the gym, now into his 60s, and that is why he continues to support our clinic to this day.

About the author

Louis A. Cona, MD

Louis A. Cona, MD

Dr. Cona has been performing stem cell therapy for over 10 years. He is a member of the World Academy of Anti-Aging Medicine (WAAAM). He is also a recognized member of the British Medical Association, the General Medical Council (UK), the Caribbean College of Family Physicians, and the American Academy of Family Physicians. He is the Medical Director for DVC Stem a world-renowned stem cell therapy clinic located in Grand Cayman.

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