What is stromal vascular fraction?

Louis A. Cona, MD
Updated on
Dec 13, 2022

Stromal vascular fraction explained by the experts at DVC Stem.

What is stromal vascular fraction?

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What is stromal vascular fraction?

Stromal Vascular Fraction (SVF) is a component of the lipoaspirate obtained from liposuction of excess adipose tissue. Lipoaspirate, the waste product of liposuction (cosmetic surgery), contains a large population of stem cells called adipose derived stem cells (ADSCs), which share a number of similarities with bone marrow stem cells, including the capacity for multilineage differentiation.

SVF is a form of stem cell therapy that is made up of stem cells harvested from adipose tissue (fat) found in our bodies. SVF cells are obtained through liposuction and contain multiple cell types, including adipose-derived stem cells (ADSCs), mesenchymal and endothelial progenitor cells, leukocyte subtypes, lymphatic cells, pericytes, and vascular smooth muscle cells. The SVF cells are processed in such a way as to contain a reproducible and consistent composition of heterogeneous cells. Upon processing and administration, the adipose-derived SVF cells can differentiate into different tissue types, support neovascularization, replace cells and repair injured issue. Although SVF has been quite popular is recent years, DVC Stem has found that using cord tissue is superior due to the many benefits it can encompass.

DVC Stem uses cord tissue-derived mesenchymal stem cells sourced from US-donated, full term human umbilical cords. While other common sources of stem cells are fat tissue or bone marrow taken from the patient directly, there are many benefits to using cord tissue. Cord tissue-derived cells are essentially "new", in their most primal state, free from the effects of aging or disease. Stem cells age as we age, and cells taken from a patient are affected by the condition of the patient at the time of extraction. There is even evidence to suggest that cells extracted from patients with existing medical conditions risk reintroducing these symptoms when used in treatments. Cord tissue-derived stem cells eliminate that risk. Additionally, they are readily available, in great supply, and are minimally invasive to the patient, without the need for any extractions, free from immune rejection, and have zero risk of transferring viruses or other communicable diseases.

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