Article updated on:
December 13, 2022
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Stem cell therapy for MS
Stem cell therapy, specifically the administration of mesenchymal stem cells (MSCs) for Multiple Sclerosis has demonstrated great potential to help improve symptoms and stabilize condition progression. The immunomodulatory (ability to regulate the immune system), tissue-protective and repair-promoting properties of MSCs demonstrated in multiple models make them an attractive therapy for Multiple Sclerosis (MS) and other conditions characterized by inflammation and/or tissue injury.
MS Patients may be able to expect an increase in energy, flexibility, strength, mobility, and control of basic function. Data is also beginning the show that mesenchymal stem cells (MSCs) administered intravenously may have the ability to halt disease progression for an extended period. (2)
Stem cells target inflammation
The therapeutic uses of stem cells as a potential therapy for a variety of diseases has been immensely explored, the number of clinical trials conducted with Mesenchymal Stem Cells has increased exponentially over the past few years. (1)
Stem cells have a unique, intrinsic property that attracts them to inflammation in the body. Studies have shown that stem cells can regenerate damaged or diseased tissues, reduce inflammation and modulate the immune system promoting better health and quality of life. Mesenchymal stem cells do this by influencing tissue repair via paracrine effects (cell signaling in order to change the behaviour of existing cells) or direct cell-to-cell contact.
"MSCs are able to migrate and seed specifically into damaged tissue sites, where they can differentiate into functional cells to replace damaged or diseased cells" (4)
Mike's progress (1 month post-treatment)
Fantastic experience at DVC! The entire staff was friendly and professional and the center was clean and well maintained. Dr. Cona was knowledgeable and answered all our questions without hesitation. Frank and the others involved in the treatment process were well informed and were there for whatever we needed as well. Everything flowed nicely from start to finish.
For us, stem cells were actually a cheaper option than the Dr. recommended MS therapies that showed no promise of improvements, only the hope of halting the disease process in the current stage. My husbands treatment was on 2/24/21. Since the very next day, we have seen improvements in gait, balance, energy and stress. These are all huge because gait and balance improvements are helping him to avoid falls. He had 5 falls in February and has had none since treatment.
Before stems he was using a walking stick and had a hard time just standing still without holding onto something to balance. Since stems, not only has he been walking without assistance, he is skimming the pool, shooting hoops, bending down and getting himself back up, and a lot of other small things he has not been able to do in a long time. We're only a month out, so hoping to see even more improvements over the days and months ahead.
(1) Mao, Fei, et al. “Mesenchymal Stem Cells and Their Therapeutic Applications in Inflammatory Bowel Disease.” Oncotarget, Impact Journals LLC, 6 June 2017, https://www.ncbi.nlm.nih.gov/pubmed/28402942.