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Can stem cells help prevent Coronavirus?

Reputable laboratory in Golden, Colorado, Vitro Biopharma reports on a potential therapy of Coronavirus (COVID-19) infections by stem cell transplant. While this therapy is not a method to eradicate or cure Coronavirus, there is evidence to support the concept that infected patients may be more likely to combat and survive the infection. 

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Image produced by the National Institute of Allergy and Infectious Diseases (NIAID), this highly magnified, digitally colourized transmission electron microscopic (TEM) image highlights the particle envelope of a single, spherical-shaped, Middle East respiratory syndrome coronavirus (MERS-CoV) virion, through the process of immunolabeling, the envelope proteins, using rabbit HCoV-EMC/2012 primary antibody, and goat anti-rabbit 10nm gold particles.

David Lyons

Guest contributor

Mar 2, 2020

Louis A. Cona, MD

Medical Director of DVC Stem

Stem cell therapy clinic in Grand Cayman

Mar 2, 2020

Reputable laboratory in Golden, Colorado, Vitro Biopharma reports on a potential therapy of Coronavirus (COVID-19) infections by stem cell transplant. While this therapy is not a method to eradicate or cure Coronavirus, there is evidence to support the concept that infected patients may be more likely to combat and survive the infection. 

What is Coronavirus? (in 2020)

According to the World Health Organization (WHO) 

A Coronavirus is a broad family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). A coronavirus can be transmitted between different species of animals, including from animals to humans.  

What are the signs and symptoms of COVID-19?

The symptoms of COVID-19 are similar to those of other Coronaviruses.  

Symptoms include: 

  • Fever
  • Cough
  • Shortness of Breath
  • Difficulty Breathing

Stem cells may be able to help the body resist Coronavirus.

Firstly, stem cells combat viral attack by the expression of specific genes known as interferon-gamma stimulated genes (ISGs). These are expressed in stem cells before their differentiation. (Wu, X, et al., Cell 172: 423, 2018). 

Hence, stem cells are expected to survive even if transplanted into a patient with an active Coronavirus infection. Also, it is known that stem cells rejuvenate and regenerate cells in the body through various processes involving reduction of inflammation, secretion of substances that protect cells, transfer of mitochondria, reduction of cell death, anti-oxidative effects and improvement of immune system function. These effects are likely to increase survival in patients infected with Coronavirus. Also, there is direct evidence of stem cell protection against viral infection. Influenza virus A/H5N1 causes acute lung injury that was reduced by human mesenchymal stromal cells (MSCs) in mice, and the treatment increased survival (Chan et al., PNAS 113:3621, 2016).

Vitro Biopharma has operated a highly regulated, FDA-compliant commercial biologics manufacturing facility for several years and is cGMP compliant, ISO9001 Certified, ISO13485 Certified, CLIA Certified and FDA registered. All clinical manufacturing occurs in a certified sterile clean room with extensive and advanced testing to assure the absence of contamination. 

Furthermore, in numerous patients treated to date by IV infusion of their Mesenchymal Stem Cells, there have been no significant adverse events while we have gained evidence of efficacy. 


Dr. Jim Musick, CEO, states:

"We presently supply our Mesenchymal Stem Cells to DVC Stem in the Cayman Islands for treatment of inflammatory conditions. We are pleased to be positioned to offer stem cell therapy for Coronavirus infection. While there are several factors related to the possible extent of this global infection, stem cell therapy represents a therapeutic option to fight the virus and increase survival, while effective vaccines are being developed. Our existing offshore partners offer stem cell transplant services, and we are in contact with CDC officials regarding potential US-based stem cell transplants into infected individuals."


About Vitro Biopharma

Vitro Biopharma, for over ten years, has supplied major biopharmaceutical firms, elite university laboratories and clinical trials worldwide with Mesenchymal Stem Cells, the MSC-Grow™ Brand of cell culture media, various stem cell derivatives and stem cell-derived differentiated cells. We also manufacture primary fibroblast cells and an expanding line of cancer-associated fibroblasts (CAFs) from various tumours, including lung, breast, melanoma, pancreatic, glioblastoma and colorectal tissues.

Out of our years of research, Vitro Biopharma has developed a patent-pending and proprietary line of umbilical cord-derived stem cellsnow being used in offshore regenerative medicine clinical trials. Their stem cells are used in regenerative medicine clinical trials with our partner DVC Stem in the Cayman Islands.


SOURCE: Vitro Diagnostics, Inc.

View source version on accesswire.com

https://www.accesswire.com/578276/Stem-Cell-Therapy-for-Coronavirus-Infection

Additional References:

(1) Coronavirus. (n.d.). Retrieved from https://www.who.int/health-topics/coronavirus

(2) Chan, M. C. W., Kuok, D. I. T., Leung, C. Y. H., Hui, K. P. Y., Valkenburg, S. A., Lau, E. H. Y., … Peiris, J. S. M. (2016, March 29). Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo. Retrieved from https://www.pnas.org/content/113/13/3621

(3) Wu, X., Dao Thi, V. L., Huang, Y., Billerbeck, E., Saha, D., Hoffmann, H.-H., … Rice, C. M. (2018, January 25). Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/29249360

"Dr. Cona is a leading edge stem cell treatment physician"

Matthew Murry - MS Patient

2 DAYS POST TREATMENT

"Is the video I posted from this morning! My speech is so easy for me now, got easier throughout the day! I can talk like a NYer (fast) for the first time in years! Praise God!"

- Matthew Murry

3 DAYS POST TREATMENT

Tyler explains his experience at DVC Stem in the Cayman Islands.

Tyler is optimistic that he will see positive results post treatment.

"The cool thing about the Cayman Islands besides being beautiful, it was an opportunity to get some rest and relaxation allowing my body to heal and restore. I'm back in the US now and feel like I am ready to conquer the world."

- Tyler Heid

2 WEEKS POST TREATMENT

2 weeks post treatment, MS patient Tyler is beginning to see amazing progress. He has been wheelchair bound for the last year and has not been able to move his legs unassisted before now.

Tyler Heid, lifting his foot 12" off the ground with 2 lb weights on his ankles.

Tyler - 2 weeks post treatment

"I'm on a path of progression and I'm getting better and better each day."

Tyler Heid - 2 months post treatment

2 MONTHS POST TREATMENT

Tyler updates about his progress, explaining the amazing response he has been receiving from his friends and family.

"People coming up to me saying I am moving, talking and smiling so much better. They are noticing a lot of things that have improved over the course of 3 months."

"This morning I was able to do things that I was unable to do before, I was able to stand up and lift my leg higher than I ever have before."

5 MONTHS POST TREATMENT

5 months post treatment Tyler sends us an update on his progress.

"I'm able to smile better, I have more control over the left side of my face."

"I have an increased ability to grip, lift my legs higher and higher which has gone well."

Tyler is optimistic and on the right track to recovery. We are ecstatic to see his progress and look forward to more updates from him.

"I have an increased ability to grip, lift my legs higher and higher which has gone well."

Tyler Heid - 5 months post treatment

EXCITING IMPROVEMENTS

Only 3 days after treatment, Matthew is now able to touch his nose with his eyes closed as well as touch his thumb and pinky together. Both of which he was previously unable to do before treatment.

We are excited to see his continued progress. His story will be updated here so keep an eye out!

Matthew showing his progress with mobility

Matthew Murry - 3 days post treatment

"This is exciting stuff, god bless"

Matthew Murry - MS Patient

2 WEEKS POST TREATMENT

Matthew experiences sensation in the bottom of his feet after receiving a simple nerve test.

His left foot did not experience any sensation or move at all, but what happened to his right foot is extremely exciting!

50 DAYS POST TREATMENT

Matthew is now able to lift his leg unassisted. He was previously unable to do so.

Matthew is experiencing the benefits of stem cell therapy first hand. You can view his progress video here.


Matthew showing some amazing mobility improvements.

Matthew Murry - 50 days post treatment

"Amazing progress from one of our MS patients Matthew Murray"

Louis A. Cona, MD - DVC Stem

3 MONTHS POST TREATMENT

Matthew is able to stand up with the assistance of stability bars.

David Lyons

Multiple Sclerosis

Although David Lyons was able to successfully fight Multiple Sclerosis through a strict regimen of diet and exercise, he wanted to ensure he was doing everything he could to stay fit. Multiple Sclerosis can be managed with treatment, but there is currently no cure for the disease. For that reason, David came to DVC Stem years ago to use the regenerative and anti-inflammatory attributes of stem cells to aid in his fight for fitness.

The positive results he experienced enabled David to stay strong in the gym, now into his 60s, and that is why he continues to support our clinic to this day.

Are you a candidate?

Complete our online application form to find out if you qualify for stem cell therapy.

APPLY FOR TREATMENT

About Our Medical DIrector

LOUIS A. CONA, MD

Dr. Cona has been performing stem cell therapy for over 10 years. He is a member of the World Academy of Anti-Aging Medicine (WAAAM). He is also a recognized member of the British Medical Association, the General Medical Council (UK), the Caribbean College of Family Physicians, and the American Academy of Family Physicians. He is the Medical Director for DVC Stem a world-renowned stem cell therapy clinic located in Grand Cayman.

Are you a candidate?

Complete our online application form to find out if you qualify for stem cell therapy.

APPLY FOR TREATMENT

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CONTACT US

info@dvcstem.com

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